Entamoeba histolytica Essays -- Essays Papers

Entamoeba histolytica everyday DescriptionEntamoeba histolytica is an ameba that feeds on cells in the human colon. It is the cause of amebic dysentery (bloody diarrhea) as well as colonic ulcerations. The infection is also referred to as amebiasis. If the organisms circularise throughout the body via the bloodstream they may cause abscesses in the liver or, less frequently, other organs.MorphologyThe organism has two forms. The vesicle is round and 10-20 micrometers in diameter, and contains four nuclei when mature. It is resistant to desiccation and stomach acid, and bathroom survive long enough in the environment to be disruption to other humans. When the vesicle reaches the large intestine, it excysts and the four nuclei present in the cyst become four separate amebae, each of which undergoes binary fission immediately thus the ingestion of a single cyst leads to 8 trophozoites. The trophozoite, 10-60 micrometers in diameter, is the active form of the organism and it is in t his form that the damage is through to the body. In 1994 the CDC recorded 2,983 cases of amebiasis in the United States. TransmissionE. histolytica is spread by the fecal-oral route. This is achieved through food or water contaminated with cysts, oral-anal familiar contact, or occasionally directly in childcare centers or institutions for the developmentally challenged. The disease is found far more frequently in sight from developing countries or travelers to such areas than in developed countries.Virulence stultification is caused by the lysis of epithelial cells, due in part to the insertion of pore-forming proteins into the membrane of the cell. Neutrophils and non-activated macrophages may also be killed and ingested by the organism, limiting the ability... ...that brings about a mucosal immune response could be trenchant. However, the lack of projected loot limits the interest of pharmaceutical and biotechnology companies. Sanitation and hygiene are effective controls bu t often cannot be applied in many unworthy nations. Until a vaccine is created and distributed, Entamoeba histolytica will remain an important disease in mortality rates, especially among children in developing countries. Referencespharmacy school information on metronidazole and other words of amebiasishttp//rxweb.nlu.edu/pharmacy/414/antiprotozoals.htmCDC MMWR from march 08 1985http//www.cdc.gov/epo/mmwr/ prevue/mmwrhtml/00000498.htmGeneral infohttp//gsbs.utmb.edu/microbook/ch079.htmWorld Health Org cost-effectiveness study on treatment of asymptomatic carriers with metronidazolehttp//www.who.int/dap-icium/posters/4p1_text.html